File:SilentSynapseFig1.jpg
Summary
Figure 1: Discrepancy between failure rates of EPSCs mediated by AMPA and NMDA receptors. EPSCs were recorded in a rat dentate granule cell in response to minimal stimulation of presynaptic axons. Twenty succesive responses are shown superimposed in each case. When holding the neuron at a negative potential to keep NMDA receptors blocked (left), AMPA receptor-mediated EPSCs were only observed in a small minority of trials. When the neuron was held at a positive potential to relieve the Mg2+ block of NMDA receptors (right), most trials resulted in an EPSC with slower kinetics typical of NMDA receptors. (Data from M.-Y. Min and D.M. Kullmann)
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 19:47, 20 December 2010 | | 391 × 191 (16 KB) | Dimitri Kullmann (Talk | contribs) | Figure 1: Discrepancy between failure rates of EPSCs mediated by AMPA and NMDA receptors. EPSCs were recorded in a rat dentate granule cell in response to minimal stimulation of presynaptic axons. Twenty succesive responses are shown superimposed in each |
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